Oxycodone: A Current Perspective on Its Pharmacology, Abuse, and Pharmacotherapeutic Developments
Additionally, avoid the use of mixed agonist/antagonist (e.g.., pentazocine, nalbuphine, and butorphanol) or partial agonist (e.g., buprenorphine) analgesics in patients who are receiving a full opioid agonist analgesic, including OXYCONTIN. oxycodone: uses, side effects, dosages, precautions In these patients, mixed agonist/antagonist and partial agonist analgesics may reduce the analgesic effect and/or may precipitate withdrawal symptoms. Do not abruptly discontinue OXYCONTIN in a patient physically dependent on opioids. Drug to Drug Interactions with Oxycodone Monitor patients receiving OXYCONTIN and any CYP3A4 inhibitor or inducer see WARNINGS AND PRECAUTIONS , DRUG INTERACTIONS , CLINICAL PHARMACOLOGY. Prolonged use of OXYCONTIN during pregnancy can...
